📌 Introduction
Antifungal drugs are important antimicrobial agents used to treat fungal infections. This topic is frequently asked in GPAT, DSSSB, and other pharmacy exams. These MCQs will help you quickly revise classification, mechanism, uses, and side effects.
📝 MCQs on Antifungal Drugs
1. Fungal infections are also called:
A) Bacteriosis
B) Mycoses
C) Virosis
D) Protozoosis
✔ Answer: B) Mycoses
2. Which is a polyene antifungal?
A) Fluconazole
B) Amphotericin B
C) Terbinafine
D) Ketoconazole
✔ Answer: B) Amphotericin B
3. Polyenes act by:
A) Inhibiting DNA
B) Binding to ergosterol
C) Blocking calcium
D) Blocking sodium
✔ Answer: B) Binding to ergosterol
4. Which drug is an azole?
A) Nystatin
B) Fluconazole
C) Caspofungin
D) Flucytosine
✔ Answer: B) Fluconazole
5. Azoles act by:
A) Increasing glucose
B) Inhibiting ergosterol synthesis
C) Increasing protein
D) Blocking calcium
✔ Answer: B) Inhibiting ergosterol synthesis
6. Which drug is an echinocandin?
A) Fluconazole
B) Terbinafine
C) Caspofungin
D) Amphotericin B
✔ Answer: C) Caspofungin
7. Echinocandins act by:
A) Blocking DNA
B) Inhibiting cell wall synthesis
C) Increasing BP
D) Blocking calcium
✔ Answer: B) Inhibiting cell wall synthesis
8. Which is an allylamine?
A) Terbinafine
B) Fluconazole
C) Amphotericin B
D) Caspofungin
✔ Answer: A) Terbinafine
9. Allylamines act by:
A) Blocking DNA
B) Inhibiting squalene epoxidase
C) Increasing BP
D) Blocking calcium
✔ Answer: B) Inhibiting squalene epoxidase
10. Flucytosine acts by:
A) Cell wall inhibition
B) DNA/RNA inhibition
C) Calcium block
D) Sodium block
✔ Answer: B) DNA/RNA inhibition
11. Which is used for systemic fungal infection?
A) Nystatin
B) Amphotericin B
C) Terbinafine
D) Clotrimazole
✔ Answer: B) Amphotericin B
12. Common side effect of antifungals:
A) Hypoglycemia
B) Nausea
C) Hypertension
D) Fever
✔ Answer: B) Nausea
13. Which causes kidney toxicity?
A) Fluconazole
B) Amphotericin B
C) Terbinafine
D) Caspofungin
✔ Answer: B) Amphotericin B
14. Azoles may cause:
A) Liver toxicity
B) Kidney failure
C) Heart attack
D) Stroke
✔ Answer: A) Liver toxicity
15. Which is used for skin infections?
A) Terbinafine
B) Insulin
C) Paracetamol
D) Aspirin
✔ Answer: A) Terbinafine
16. Which drug treats candidiasis?
A) Fluconazole
B) Insulin
C) Antibiotic
D) NSAID
✔ Answer: A) Fluconazole
17. Antifungals act on:
A) Bacteria
B) Virus
C) Fungi
D) Protozoa
✔ Answer: C) Fungi
18. Ergosterol is present in:
A) Human cells
B) Bacterial cells
C) Fungal cells
D) Plant cells
✔ Answer: C) Fungal cells
19. Which drug is topical antifungal?
A) Clotrimazole
B) Insulin
C) Antibiotic
D) Vitamin
✔ Answer: A) Clotrimazole
20. Which class inhibits cell wall?
A) Azoles
B) Echinocandins
C) Polyenes
D) Allylamines
✔ Answer: B) Echinocandins
21. Which is most potent antifungal?
A) Fluconazole
B) Amphotericin B
C) Terbinafine
D) Clotrimazole
✔ Answer: B) Amphotericin B
22. Which is used for nail infection?
A) Terbinafine
B) Insulin
C) Antibiotic
D) NSAID
✔ Answer: A) Terbinafine
23. Which inhibits ergosterol synthesis?
A) Azoles
B) Polyenes
C) Echinocandins
D) Insulin
✔ Answer: A) Azoles
24. Which drug binds ergosterol?
A) Amphotericin B
B) Fluconazole
C) Terbinafine
D) Caspofungin
✔ Answer: A) Amphotericin B
25. Which infection affects skin?
A) Ringworm
B) Diabetes
C) Cancer
D) Stroke
✔ Answer: A) Ringworm
26. Which causes headache?
A) Antifungals
B) Antibiotics
C) Insulin
D) Vitamins
✔ Answer: A) Antifungals
27. Which drug is antimetabolite?
A) Flucytosine
B) Fluconazole
C) Terbinafine
D) Amphotericin B
✔ Answer: A) Flucytosine
28. Which increases fungal cell permeability?
A) Polyenes
B) Azoles
C) Echinocandins
D) Insulin
✔ Answer: A) Polyenes
29. Antifungals are used in:
A) Viral infection
B) Bacterial infection
C) Fungal infection
D) Pain
✔ Answer: C) Fungal infection
30. Best use of antifungals:
A) Diabetes
B) Infection (fungal)
C) Pain
D) Fever
✔ Answer: B) Infection (fungal)
🎯 Conclusion
These 30 MCQs on antifungal drugs will help you revise important pharmacology concepts and boost exam preparation. Practice daily for better retention and performance.
👉 Read full notes here: https://pharmacymcq.in/antifungal-drugs-classification-mechanism-uses-side-effects/