Top 30 MCQs on Antihypertensive Drugs with Answers & Explanation

📌 Introduction

Antihypertensive drugs are widely used in the treatment of high blood pressure and are one of the most important topics in pharmacology exams like GPAT, DSSSB, and other pharmacy tests. These MCQs will help you revise classification, mechanism, uses, and side effects effectively. 

📝 MCQs on Antihypertensive Drugs

1. Hypertension is defined as BP:
A) 100/60 mmHg
B) 120/80 mmHg
C) ≥140/90 mmHg
D) 90/60 mmHg
✔ Answer: C) ≥140/90 mmHg

2. Which drug is a diuretic?
A) Amlodipine
B) Furosemide
C) Propranolol
D) Losartan
✔ Answer: B) Furosemide

3. ACE inhibitors act by:
A) Blocking calcium
B) Blocking angiotensin II formation
C) Increasing heart rate
D) Increasing sodium
✔ Answer: B) Blocking angiotensin II formation

4. Example of ACE inhibitor:
A) Losartan
B) Enalapril
C) Atenolol
D) Amlodipine
✔ Answer: B) Enalapril

5. ARBs block:
A) Calcium channels
B) Angiotensin receptors
C) Sodium
D) Potassium
✔ Answer: B) Angiotensin receptors

6. Example of ARB:
A) Enalapril
B) Losartan
C) Propranolol
D) Verapamil
✔ Answer: B) Losartan

7. Beta blockers reduce:
A) Blood sugar
B) Heart rate
C) Oxygen
D) Sodium
✔ Answer: B) Heart rate

8. Example of beta blocker:
A) Amlodipine
B) Atenolol
C) Enalapril
D) Losartan
✔ Answer: B) Atenolol

9. Calcium channel blockers act by:
A) Blocking calcium entry
B) Blocking sodium
C) Increasing potassium
D) Increasing glucose
✔ Answer: A) Blocking calcium entry

10. Example of CCB:
A) Propranolol
B) Amlodipine
C) Enalapril
D) Losartan
✔ Answer: B) Amlodipine

11. Vasodilators act by:
A) Increasing BP
B) Dilating blood vessels
C) Reducing urine
D) Increasing sugar
✔ Answer: B) Dilating blood vessels

12. Example of vasodilator:
A) Hydralazine
B) Atenolol
C) Furosemide
D) Losartan
✔ Answer: A) Hydralazine

13. ACE inhibitors cause:
A) Fever
B) Dry cough
C) Pain
D) Sleep
✔ Answer: B) Dry cough

14. ARBs have:
A) More cough
B) Less/no cough
C) High sugar
D) Infection
✔ Answer: B) Less/no cough

15. Diuretics reduce:
A) Blood volume
B) Oxygen
C) Sugar
D) Protein
✔ Answer: A) Blood volume

16. Antihypertensives are used in:
A) Cancer
B) Hypertension
C) Infection
D) Pain
✔ Answer: B) Hypertension

17. Which reduces cardiac output?
A) Beta blockers
B) Antibiotics
C) NSAIDs
D) Vitamins
✔ Answer: A) Beta blockers

18. Which causes edema?
A) ACE inhibitors
B) CCBs
C) ARBs
D) Diuretics
✔ Answer: B) CCBs

19. Which is first-line therapy?
A) Diuretics
B) Antibiotics
C) Insulin
D) Steroids
✔ Answer: A) Diuretics

20. Which drug lowers BP by vasodilation?
A) Hydralazine
B) Insulin
C) Antibiotic
D) Vitamin
✔ Answer: A) Hydralazine

21. Antihypertensives prevent:
A) Infection
B) Stroke
C) Pain
D) Fever
✔ Answer: B) Stroke

22. Which acts on RAAS system?
A) ACE inhibitors
B) Antibiotics
C) NSAIDs
D) Vitamins
✔ Answer: A) ACE inhibitors

23. Which is safest alternative to ACE inhibitor?
A) ARB
B) Beta blocker
C) CCB
D) Diuretic
✔ Answer: A) ARB

24. Beta blockers may cause:
A) Tachycardia
B) Bradycardia
C) Fever
D) Infection
✔ Answer: B) Bradycardia

25. Diuretics may cause:
A) Dehydration
B) Growth
C) Sleep
D) Energy
✔ Answer: A) Dehydration

26. Which drug relaxes blood vessels?
A) CCB
B) Antibiotic
C) Insulin
D) Vitamin
✔ Answer: A) CCB

27. Hypertension affects:
A) Heart
B) Brain
C) Kidney
D) All
✔ Answer: D) All

28. Which reduces blood pressure?
A) Antihypertensives
B) Antibiotics
C) NSAIDs
D) Hormones
✔ Answer: A) Antihypertensives

29. Which drug group blocks calcium?
A) CCB
B) ARB
C) ACE
D) Diuretics
✔ Answer: A) CCB

30. Best use of antihypertensives:
A) Infection
B) Hypertension
C) Diabetes
D) Cancer
✔ Answer: B) Hypertension

🎯 Conclusion

These 30 MCQs on antihypertensive drugs will help you revise important pharmacology concepts and improve your exam performance. Practice regularly for GPAT and DSSSB success.

👉 Read full notes here:https://pharmacymcq.in/antihypertensive-drugs-classification-mechanism-uses-side-effects/

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