📌Introduction
Antibiotics are one of the most important topics in pharmacology and are frequently asked in exams like GPAT, DSSSB, and other pharmacy competitive exams. These MCQs will help you revise important concepts like classification, mechanism, uses, and resistance.
🧬 MCQs on Antibiotics
1. Antibiotics are used to treat:
A) Viral infections
B) Bacterial infections
C) Fungal infections
D) Parasitic infections
✔ Answer: B) Bacterial infections
➜ Explanation: Antibiotics act only against bacteria.
2. Which is a bactericidal drug?
A) Penicillin
B) Tetracycline
C) Erythromycin
D) Chloramphenicol
✔ Answer: A) Penicillin
➜ Explanation: It kills bacteria by inhibiting cell wall synthesis.
3. Penicillin acts by inhibiting:
A) Protein synthesis
B) DNA synthesis
C) Cell wall synthesis
D) Metabolism
✔ Answer: C) Cell wall synthesis
4. Tetracycline inhibits:
A) DNA synthesis
B) Protein synthesis
C) Cell wall synthesis
D) RNA synthesis
✔ Answer: B) Protein synthesis
5. Ciprofloxacin acts on:
A) Ribosome
B) DNA gyrase
C) Cell wall
D) Enzymes
✔ Answer: B) DNA gyrase
6. Sulfonamides act as:
A) Protein inhibitors
B) Cell wall inhibitors
C) Antimetabolites
D) Hormones
✔ Answer: C) Antimetabolites
7. Which antibiotic is used in tuberculosis?
A) Amoxicillin
B) Rifampicin
C) Ibuprofen
D) Paracetamol
✔ Answer: B) Rifampicin
8. Macrolides act on:
A) Cell wall
B) Protein synthesis
C) DNA
D) Hormones
✔ Answer: B) Protein synthesis
9. Aminoglycosides are:
A) Bacteriostatic
B) Bactericidal
C) Antifungal
D) Antiviral
✔ Answer: B) Bactericidal
10. Chloramphenicol inhibits:
A) 30S ribosome
B) 50S ribosome
C) DNA
D) Cell wall
✔ Answer: B) 50S ribosome
11. Which antibiotic causes teeth discoloration?
A) Penicillin
B) Tetracycline
C) Ciprofloxacin
D) Rifampicin
✔ Answer: B) Tetracycline
12. Which is NOT an antibiotic?
A) Penicillin
B) Ciprofloxacin
C) Paracetamol
D) Rifampicin
✔ Answer: C) Paracetamol
13. Antibiotics should be avoided in:
A) Bacterial infection
B) Viral infection
C) Fever
D) Pain
✔ Answer: B) Viral infection
14. Resistance occurs due to:
A) Proper use
B) Overuse
C) Correct dose
D) Full course
✔ Answer: B) Overuse
15. Which inhibits DNA replication?
A) Penicillin
B) Ciprofloxacin
C) Tetracycline
D) Erythromycin
✔ Answer: B) Ciprofloxacin
16. Erythromycin belongs to:
A) Penicillin
B) Macrolide
C) Aminoglycoside
D) Tetracycline
✔ Answer: B) Macrolide
17. Which is bacteriostatic?
A) Penicillin
B) Aminoglycosides
C) Tetracycline
D) Cephalosporin
✔ Answer: C) Tetracycline
18. Cephalosporins act on:
A) Protein
B) Cell wall
C) DNA
D) RNA
✔ Answer: B) Cell wall
19. Superinfection is due to:
A) Low dose
B) Destruction of normal flora
C) High immunity
D) Infection
✔ Answer: B) Destruction of normal flora
20. Antibiotics may cause:
A) Allergy
B) Growth
C) Energy
D) Sleep
✔ Answer: A) Allergy
21. Which is broad-spectrum antibiotic?
A) Penicillin G
B) Tetracycline
C) Rifampicin
D) Vancomycin
✔ Answer: B) Tetracycline
22. Which is narrow spectrum?
A) Penicillin G
B) Tetracycline
C) Chloramphenicol
D) Ciprofloxacin
✔ Answer: A) Penicillin G
23. Fluoroquinolones act on:
A) DNA
B) Protein
C) Cell wall
D) Metabolism
✔ Answer: A) DNA
24. Which antibiotic is nephrotoxic?
A) Aminoglycosides
B) Penicillin
C) Tetracycline
D) Macrolide
✔ Answer: A) Aminoglycosides
25. Which is used in UTI?
A) Ciprofloxacin
B) Insulin
C) Aspirin
D) Vitamin D
✔ Answer: A) Ciprofloxacin
26. Which causes ototoxicity?
A) Aminoglycosides
B) Penicillin
C) Macrolides
D) Sulfonamides
✔ Answer: A) Aminoglycosides
27. Which is a macrolide?
A) Erythromycin
B) Penicillin
C) Ciprofloxacin
D) Tetracycline
✔ Answer: A) Erythromycin
28. Which antibiotic affects bone growth?
A) Tetracycline
B) Penicillin
C) Rifampicin
D) Amoxicillin
✔ Answer: A) Tetracycline
29. Antibiotics act on:
A) Viruses
B) Bacteria
C) Fungi
D) Parasites
✔ Answer: B) Bacteria
30. Best use of antibiotics:
A) Viral fever
B) Bacterial infection
C) Pain
D) Diabetes
✔ Answer: B) Bacterial infection
📝 Conclusion
These 30 MCQs on antibiotics will help you strengthen your pharmacology concepts and improve your exam performance. Practice regularly for better results in GPAT and DSSSB exams.
👉 Read detailed notes here: https://pharmacymcq.in/antibiotics-classification-mechanism-uses-side-effects/