Top 30 MCQs on Cholinergic Drugs with Answers

📌 Introduction

Cholinergic drugs stimulate cholinergic receptors or increase the action of acetylcholine in the body. These drugs mainly mimic parasympathetic nervous system activity and are used in glaucoma, myasthenia gravis, urinary retention, and Alzheimer’s disease. Cholinergic drugs are highly important for GPAT, DSSSB, PCI, and other pharmacy examinations.

📝 MCQs

1. Cholinergic drugs are also known as:
A) Sympathomimetics
B) Parasympathomimetics
C) Sedatives
D) Antihistamines
✔ Answer: B

—

2. Natural neurotransmitter for cholinergic receptors:
A) Dopamine
B) Adrenaline
C) Acetylcholine
D) Histamine
✔ Answer: C

—

3. Muscarinic receptors are mainly present in:
A) Skeletal muscles only
B) Heart and glands
C) Bone marrow
D) Liver only
✔ Answer: B

—

4. Nicotinic receptors are mainly present in:
A) Smooth muscles only
B) Skeletal muscles and autonomic ganglia
C) Kidney only
D) Skin only
✔ Answer: B

—

5. Cholinergic drugs mainly mimic:
A) Sympathetic activity
B) Parasympathetic activity
C) CNS depression
D) Sedative action
✔ Answer: B

—

6. Which drug is a direct acting cholinergic agonist?
A) Neostigmine
B) Physostigmine
C) Pilocarpine
D) Donepezil
✔ Answer: C

—

7. Neostigmine belongs to:
A) Adrenergic agonists
B) Anticholinesterase drugs
C) Sedatives
D) Antipsychotics
✔ Answer: B

—

8. Pilocarpine is mainly used in:
A) Diabetes
B) Glaucoma
C) Asthma
D) Hypertension
✔ Answer: B

—

9. Bethanechol is used in:
A) Urinary retention
B) Migraine
C) Fever
D) Hypertension
✔ Answer: A

—

10. Donepezil is used in:
A) Tuberculosis
B) Alzheimer’s disease
C) Ulcer
D) Asthma
✔ Answer: B

—

11. Cholinergic drugs cause:
A) Tachycardia
B) Bradycardia
C) Hypertension
D) Bronchodilation
✔ Answer: B

—

12. Muscarinic receptor stimulation causes:
A) Pupil dilation
B) Miosis
C) Bronchodilation
D) Increased heart rate
✔ Answer: B

—

13. Excess cholinergic stimulation may produce:
A) Dry mouth
B) Constipation
C) Excessive salivation
D) Tachycardia
✔ Answer: C

—

14. Indirect acting cholinergic drugs work by:
A) Blocking acetylcholine release
B) Inhibiting acetylcholinesterase
C) Blocking adrenergic receptors
D) Increasing dopamine release
✔ Answer: B

—

15. Pyridostigmine is commonly used in:
A) Asthma
B) Myasthenia gravis
C) Hypertension
D) Ulcer
✔ Answer: B

—

16. Cholinergic drugs increase:
A) GI motility
B) Heart rate
C) Blood pressure
D) Bronchodilation
✔ Answer: A

—

17. Which effect is produced by muscarinic stimulation?
A) Bronchodilation
B) Reduced glandular secretion
C) Increased salivation
D) Increased blood glucose
✔ Answer: C

—

18. Cholinergic drugs may cause:
A) Diarrhea
B) Constipation
C) Tachycardia
D) Hyperglycemia
✔ Answer: A

—

19. Which receptor is involved in skeletal muscle contraction?
A) Muscarinic receptor
B) Nicotinic receptor
C) Dopamine receptor
D) Histamine receptor
✔ Answer: B

—

20. Acetylcholinesterase enzyme normally:
A) Produces acetylcholine
B) Breaks down acetylcholine
C) Blocks receptors
D) Increases dopamine
✔ Answer: B

—

21. Cholinergic drugs reduce:
A) GI secretion
B) Heart rate
C) Urinary bladder contraction
D) Salivation
✔ Answer: B

—

22. Which drug is an anticholinesterase agent?
A) Pilocarpine
B) Neostigmine
C) Adrenaline
D) Salbutamol
✔ Answer: B

—

23. Cholinergic drugs should be used cautiously in:
A) Asthma
B) Healthy adults
C) Mild fever
D) Common cold
✔ Answer: A

—

24. Excessive cholinergic activity may cause:
A) Bronchodilation
B) Bronchospasm
C) Mydriasis
D) Tachycardia
✔ Answer: B

—

25. Which receptor causes glandular secretion?
A) Muscarinic receptor
B) β1 receptor
C) α1 receptor
D) Dopamine receptor
✔ Answer: A

—

26. Cholinergic drugs are contraindicated in:
A) Severe asthma
B) Healthy adults
C) Mild headache
D) Fever
✔ Answer: A

—

27. Which condition uses neostigmine?
A) Myasthenia gravis
B) Migraine
C) Asthma
D) Hypertension
✔ Answer: A

—

28. Cholinergic drugs cause:
A) Bronchodilation
B) Bronchoconstriction
C) Increased blood pressure
D) Hyperglycemia
✔ Answer: B

—

29. Main action of cholinergic drugs:
A) Stimulate sympathetic nervous system
B) Stimulate parasympathetic nervous system
C) Produce CNS depression
D) Block neurotransmitters
✔ Answer: B

—

30. Which drug is used to increase bladder contraction?
A) Salbutamol
B) Bethanechol
C) Adrenaline
D) Aspirin
✔ Answer: B

🎯 Conclusion

These MCQs help in quick revision of cholinergic drugs for GPAT, DSSSB, PCI, and other pharmacy examinations.

👉 Read full notes here: https://pharmacymcq.in/cholinergic-drugs-classification-mechanism-uses-side-effects/