Top 30 MCQs on Anticholinergic Drugs with Answers & Explanation

📌 Introduction

Anticholinergic drugs block the action of acetylcholine at muscarinic receptors and suppress parasympathetic nervous system activity. These drugs are widely used in asthma, COPD, motion sickness, Parkinson’s disease, and organophosphate poisoning. Anticholinergic drugs are highly important for GPAT, DSSSB, PCI, and other pharmacy examinations.

📝 MCQs

1. Anticholinergic drugs are also known as:
A) Sympathomimetics
B) Parasympathomimetics
C) Parasympatholytics
D) Sedatives
✔ Answer: C

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2. Anticholinergic drugs mainly block:
A) Dopamine receptors
B) Histamine receptors
C) Muscarinic receptors
D) Adrenergic receptors
✔ Answer: C

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3. Natural neurotransmitter blocked by anticholinergic drugs:
A) Adrenaline
B) Acetylcholine
C) Dopamine
D) Serotonin
✔ Answer: B

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4. Atropine belongs to:
A) Cholinergic agonists
B) Natural anticholinergic alkaloids
C) β blockers
D) Sedatives
✔ Answer: B

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5. Scopolamine is commonly used for:
A) Hypertension
B) Motion sickness
C) Diabetes
D) Fever
✔ Answer: B

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6. Ipratropium is mainly used in:
A) Asthma and COPD
B) Tuberculosis
C) Ulcer
D) Migraine
✔ Answer: A

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7. Anticholinergic drugs cause:
A) Increased salivation
B) Bronchoconstriction
C) Bronchodilation
D) Bradycardia
✔ Answer: C

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8. Which effect is produced by atropine?
A) Miosis
B) Mydriasis
C) Excess sweating
D) Increased GI motility
✔ Answer: B

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9. Anticholinergic drugs generally cause:
A) Bradycardia
B) Tachycardia
C) Hypotension
D) Bronchospasm
✔ Answer: B

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10. Tropicamide is used in:
A) Ophthalmic examination
B) Hypertension
C) Diabetes
D) Asthma
✔ Answer: A

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11. Anticholinergic drugs reduce:
A) Heart rate
B) Salivation
C) Bronchodilation
D) Blood glucose
✔ Answer: B

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12. Which drug is used in organophosphate poisoning?
A) Atropine
B) Salbutamol
C) Aspirin
D) Adrenaline
✔ Answer: A

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13. Trihexyphenidyl is used in:
A) Asthma
B) Parkinson’s disease
C) Ulcer
D) Tuberculosis
✔ Answer: B

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14. Anticholinergic drugs produce:
A) Increased GI motility
B) Reduced GI motility
C) Excess lacrimation
D) Bronchospasm
✔ Answer: B

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15. Which condition requires cautious use of anticholinergic drugs?
A) Glaucoma
B) Healthy adults
C) Fever
D) Common cold
✔ Answer: A

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16. Common side effect of anticholinergic drugs:
A) Excess salivation
B) Dry mouth
C) Diarrhea
D) Sweating
✔ Answer: B

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17. Anticholinergic drugs may cause:
A) Urinary retention
B) Excess urination
C) Hypoglycemia
D) Bradycardia
✔ Answer: A

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18. Which receptor is blocked by atropine?
A) Muscarinic receptor
B) Dopamine receptor
C) β receptor
D) Nicotinic receptor
✔ Answer: A

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19. Anticholinergic drugs inhibit:
A) Sympathetic activity
B) Parasympathetic activity
C) Skeletal muscle activity only
D) CNS stimulation only
✔ Answer: B

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20. Scopolamine is useful in preventing:
A) Hypertension
B) Motion sickness
C) Diabetes
D) Asthma
✔ Answer: B

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21. Anticholinergic drugs may cause:
A) Constipation
B) Diarrhea
C) Increased sweating
D) Bradycardia
✔ Answer: A

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22. Which drug is a bronchodilator anticholinergic?
A) Ipratropium
B) Neostigmine
C) Pilocarpine
D) Donepezil
✔ Answer: A

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23. Atropine causes:
A) Increased secretions
B) Reduced secretions
C) Increased GI motility
D) Bronchospasm
✔ Answer: B

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24. Which ocular effect is caused by anticholinergic drugs?
A) Miosis
B) Mydriasis
C) Reduced pupil size
D) Lacrimation
✔ Answer: B

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25. Anticholinergic drugs are contraindicated in:
A) Angle-closure glaucoma
B) Healthy adults
C) Mild fever
D) Common cold
✔ Answer: A

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26. Dicyclomine is mainly used as:
A) Antispasmodic
B) Antidepressant
C) Antibiotic
D) Sedative
✔ Answer: A

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27. Anticholinergic drugs may decrease:
A) Sweating
B) Heart rate
C) Blood glucose
D) Bronchodilation
✔ Answer: A

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28. Main action of anticholinergic drugs:
A) Stimulate parasympathetic system
B) Block parasympathetic system
C) Stimulate adrenergic receptors
D) Increase acetylcholine release
✔ Answer: B

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29. Which drug is used before surgery to reduce secretions?
A) Atropine
B) Aspirin
C) Salbutamol
D) Metformin
✔ Answer: A

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30. Anticholinergic drugs mainly act opposite to:
A) Adrenergic drugs
B) Cholinergic drugs
C) Antihistamines
D) Sedatives
✔ Answer: B

🎯 Conclusion

These MCQs help in quick revision of anticholinergic drugs for GPAT, DSSSB, PCI, and other pharmacy examinations.

👉 Read full notes here: https://pharmacymcq.in/anticholinergic-drugs-classification-mechanism-uses/