Top 30 MCQs on Antiulcer Drugs with Answers & Explanation

📌 Introduction  

Antiulcer drugs are widely used to treat peptic ulcer disease and acid-related disorders. They work by reducing gastric acid secretion or protecting the gastric mucosa. This topic is very important for GPAT, DSSSB, and other pharmacy exams.

 📝 MCQs  

1. Proton pump inhibitors act by:  

A) Blocking H1 receptors  

B) Inhibiting H⁺/K⁺ ATPase  

C) Neutralizing acid  

D) Increasing mucus  

✔ Answer: B  

2. Example of PPI:  

A) Ranitidine  

B) Omeprazole  

C) Sucralfate  

D) Kaolin  

✔ Answer: B  

3. H2 receptor blockers act by:  

A) Blocking histamine receptors  

B) Neutralizing acid  

C) Increasing secretion  

D) Blocking dopamine  

✔ Answer: A  

4. Example of H2 blocker:  

A) Omeprazole  

B) Ranitidine  

C) Senna  

D) Loperamide  

✔ Answer: B  

5. Antacids act by:  

A) Reducing motility  

B) Neutralizing gastric acid  

C) Blocking receptors  

D) Increasing secretion  

✔ Answer: B  

6. Example of antacid:  

A) Magnesium hydroxide  

B) Omeprazole  

C) Sucralfate  

D) Famotidine  

✔ Answer: A  

7. Cytoprotective agent:  

A) Sucralfate  

B) Ranitidine  

C) Omeprazole  

D) Kaolin  

✔ Answer: A  

8. Misoprostol acts by:  

A) Blocking acid  

B) Increasing mucus production  

C) Reducing motility  

D) Binding toxins  

✔ Answer: B  

9. Main use of antiulcer drugs:  

A) Infection  

B) Peptic ulcer  

C) Diabetes  

D) Fever  

✔ Answer: B  

10. GERD stands for:  

A) Gastric enzyme reaction disease  

B) Gastroesophageal reflux disease  

C) General enzyme reaction disorder  

D) Gastric reflux disorder  

✔ Answer: B  

11. Which gives immediate relief?  

A) PPI  

B) Antacid  

C) H2 blocker  

D) Antibiotic  

✔ Answer: B  

12. Long-term PPI use may cause:  

A) Hypertension  

B) Vitamin B12 deficiency  

C) Diabetes  

D) Fever  

✔ Answer: B  

13. H2 blockers reduce:  

A) Acid secretion  

B) Motility  

C) Absorption  

D) Pain  

✔ Answer: A  

14. PPIs are best for:  

A) Immediate relief  

B) Strong acid suppression  

C) Infection  

D) Pain  

✔ Answer: B  

15. Sucralfate acts by:  

A) Neutralizing acid  

B) Coating ulcer surface  

C) Blocking receptors  

D) Increasing motility  

✔ Answer: B  

16. Which drug protects mucosa?  

A) Sucralfate  

B) Ranitidine  

C) Omeprazole  

D) Loperamide  

✔ Answer: A  

17. Which condition uses antiulcer drugs?  

A) Diarrhea  

B) Constipation  

C) Ulcer  

D) Fever  

✔ Answer: C  

18. Zollinger-Ellison syndrome involves:  

A) Low acid  

B) High acid secretion  

C) Infection  

D) Pain  

✔ Answer: B  

19. Side effect of antacids:  

A) Constipation/diarrhea  

B) Fever  

C) Pain  

D) Infection  

✔ Answer: A  

20. Which is strongest acid inhibitor?  

A) Antacid  

B) PPI  

C) H2 blocker  

D) Vitamin  

✔ Answer: B  

21. Ranitidine belongs to:  

A) PPI  

B) H2 blocker  

C) Antacid  

D) Laxative  

✔ Answer: B  

22. Omeprazole belongs to:  

A) H2 blocker  

B) PPI  

C) Antacid  

D) Antibiotic  

✔ Answer: B  

23. Misoprostol is:  

A) PPI  

B) Prostaglandin analog  

C) Antacid  

D) Antibiotic  

✔ Answer: B  

24. Which reduces gastric acid most effectively?  

A) Antacid  

B) PPI  

C) H2 blocker  

D) Sucralfate  

✔ Answer: B  

25. Which neutralizes acid?  

A) Antacid  

B) PPI  

C) H2 blocker  

D) Antibiotic  

✔ Answer: A  

26. Which drug is used in GERD?  

A) PPI  

B) Insulin  

C) Antibiotic  

D) Vitamin  

✔ Answer: A  

27. Which drug blocks histamine action?  

A) H2 blocker  

B) PPI  

C) Antacid  

D) Laxative  

✔ Answer: A  

28. Which drug increases mucus?  

A) Misoprostol  

B) Omeprazole  

C) Ranitidine  

D) Kaolin  

✔ Answer: A  

29. Which drug coats ulcer?  

A) Sucralfate  

B) Omeprazole  

C) Ranitidine  

D) Magnesium hydroxide  

✔ Answer: A  

30. Best treatment for severe ulcers:  

A) Antacid  

B) PPI  

C) Vitamin  

D) Antibiotic  

✔ Answer: B  

🎯 Conclusion  

These MCQs help you revise antiulcer drugs quickly and effectively for exams.

👉 Read full notes here: https://pharmacymcq.in/antiulcer-drugs-classification-mechanism-uses/

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